Plasmapheresis for the Treatment of Anti-M Alloimmunization in Pregnancy

Table 1

Course of treatment of selective plasma exchange, anti-M titers, and the peak systolic velocity in the middle cerebral artery.

Gestational age	SePE	Anti-M antibody titer		MCA-PSV; (MoM)
		Pre SePE	Post SePE
13 5/7		128
14 4/7	1				SePE 2/week
15 0/7	2	512	128
15 4/7	3
16 0/7	4	64	32		SePE 1/week
17 0/7	5	64	32
18 0/7	6	64	32	1.01
19 0/7	7	64	32	0.97
20 0/7	8	256	256	1.01
21 0/7	9	256	256	0.86
22 0/7	10	256	256	0.85
23 1/7	11	128	64	0.95	SePE 2/week
23 5/7	12	256	128	1.03
24 1/7	13	256	128
24 3/7	14	128	64	1.01
24 6/7	15	128	64
25 4/7	16	64	64	1.27
26 0/7	17	64	64	1.01
26 4/7	18	128	64
27 0/7	19	256	128
27 4/7	20	128	32	1.56
28 0/7	21	512	256	1.24
28 4/7	22	256	256	1.6
28 6/7				1.5	IUT
29 0/7	23	128	128	1.24
29 4/7	24	256	64	1.3
30 0/7	25	256	128	1.48
31 0/7				1.27	Delivery

SePE: selective plasma exchange; MCA-PSV: the peak systolic velocity in the middle cerebral artery; MoM: multiples of median; IUT: intrauterine blood transfusion.