Low-Malignant Schwannoma of the Cervix in Pregnancy: A Case Report and Literature Systematic Review

Table 1

Published cases of cervical schwannomas.

Author	Age	Presentation	Pathology	Treatment	Outcome
Cid [16]	NA	NA	Benign schwannosis	NA	NA
Gwavava [11]	38	Nodule	Benign schwannoma	DE	NA
Terzakis [12]	47	Nodule	Melanocytic schwannoma	TAH	NED; 3 years FU
LeMaire [17]	47	Nodule	Benign schwannoma	LEEP	NED; 6 months FU
Tahmasbi [3]	48	Uterine mass	Benign schwannoma	TAH BSO	NA
Sloan [18]	47	AVB	Malignant schwannoma	TAH BSO	NED; 1 year FU
Junge [19]	41	AVB	Malignant schwannoma	TAH PLNS	NA
Keel [20]	25/65/73	1 & 2: AVB; 3: polyp	Malignant schwannoma	TAH	1 & 2: NA; 3: DP
Lallas [13]	51	AVB	Malignant schwannoma	TAH BSO	NED; 1 year FU
Bernstein [9]	65	AVB	Malignant schwannoma	RH PPLND	NA
Di Giovannantonio [15]	27	AVB	Malignant schwannoma	TAH	NED; 3 years FU
Kim [21]	50	Polyp	Malignant schwannoma	RH BSO PLND ACT	DP LFU
Dong [14]	45	AVB	Malignant schwannoma	LRH BSO PLND	NA
Dey [4]	37	Polyp, AVB	Benign schwannoma	D&C	NED; 6 months FU
Present case	32	Nodule	Low-malignant schwannoma	LEEP-VT	NED; 6 years FU

ACT: adjuvant chemotherapy; AVB: abnormal vaginal bleeding; BSO: bilateral salpingo-oophorectomy; DE: diathermy excision; D&C: dilation and curettage; DP: disease progression; FU: follow-up; LEEP: loop electrosurgical excision procedure; LFU: lost at follow-up; NA: not available; NED: no evidence of disease; PLND: pelvic lymph node dissection; PLNS: pelvic lymph node sampling; PPLND: pelvic and periaortic lymph node dissection; RH: radical hysterectomy; TAH: total abdominal hysterectomy; VT: vaginal trachelectomy.