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Case Reports in Oncological Medicine
Volume 2012, Article ID 520430, 5 pages
http://dx.doi.org/10.1155/2012/520430
Case Report

A Case of a Metastatic Disease to the Pancreas from a Small-Cell Lung Carcinoma Documented by a CT-Scan-Guided Trucut Biopsy: The Diagnostic Role of Cytomorphology and Immunohistochemistry

1Department of Medical Oncology, Hassan II University Hospital, Fez, Morocco
2Department of Pathology, Hassan II University Hospital, Fez, Morocco

Received 30 July 2012; Accepted 25 September 2012

Academic Editors: M. Ryberg and G. P. Vandoros

Copyright © 2012 N. Bouyahia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. F. Cook, Y. E. Miller, and P. A. Bunn Jr., “Small cell lung cancer: etiology, biology, clinical features, staging, and treatment,” Current Problems in Cancer, vol. 17, no. 2, pp. 69–141, 1993. View at Google Scholar · View at Scopus
  2. A. Schwendel, H. Langreck, M. Reichel et al., “Primary small-cell lung carcinomas and their metastases are characterized by a recurrent pattern of genetic alterations,” International Journal of Cancer, vol. 74, pp. 86–93, 1997. View at Google Scholar
  3. S. Xi-Wen and C. Shu-Zhen, “Characterization of pancreatic metastases from primary lung cancer using magnetic resonance imaging,” Clinical Imaging, vol. 34, no. 5, pp. 351–354, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. I. B. Jeong, S. M. Kim, T. H. Lee et al., “Pancreatic metastasis and obstructive jaundice in small cell lung carcinoma,” Korean Journal of Internal Medicine, vol. 21, no. 2, pp. 132–135, 2006. View at Google Scholar · View at Scopus
  5. H. J. Shin and N. P. Caraway, “Fine-needle aspiration biopsy of metastatic small cell carcinoma from extra pulmonary sites,” Diagnostic Cytopathology, vol. 19, pp. 177–181, 1998. View at Google Scholar
  6. L. J. Layfield, S. L. Hirschowitz, and D. G. Adler, “Metastatic disease to the pancreas documented by endoscopic ultrasound guided fine-needle aspiration: a seven-year experience,” Diagnostic Cytopathology, vol. 40, no. 3, pp. 228–233, 2010. View at Google Scholar
  7. K. Koito, T. Namieno, T. Nagakawa, T. Shyonai, N. Hirokawa, and K. Morita, “Solitary cystic tumor of the pancreas: EUS-pathologic correlation,” Gastrointestinal Endoscopy, vol. 45, no. 3, pp. 268–276, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. N. V. Adsay, A. Andea, O. Basturk, N. Kilinc, H. Nassar, and J. D. Cheng, “Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature,” Virchows Archiv, vol. 444, no. 6, pp. 527–535, 2004. View at Google Scholar · View at Scopus
  9. T. Maeno, H. Satoh, H. Ishikawa et al., “Patterns of pancreatic metastasis from lung cancer,” Anticancer Research, vol. 18, no. 4, pp. 2881–2884, 1998. View at Google Scholar · View at Scopus
  10. W. J. Yoon, J. K. Ryu, Y. T. Kim, Y. B. Yoon, S. W. Kim, and W. H. Kim, “Clinical features of metastatic tumors of the pancreas in Korea: a single-center study,” Gut and Liver, vol. 5, no. 1, pp. 61–64, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. J. S. Woo, K. R. Joo, Y. S. Woo et al., “Pancreatitis from metastatic small cell lung cancer: successful treatment with endoscopic intrapancreatic stenting,” Korean Journal of Internal Medicine, vol. 21, no. 4, pp. 256–261, 2006. View at Google Scholar · View at Scopus
  12. C. M. Schmidt, E. S. Powell, C. T. Yiannoutsos et al., “Pancreaticoduodenectomy: a 20-year experience in 516 patients,” Archives of Surgery, vol. 139, no. 7, pp. 718–727, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Di Stasi, R. Lencioni, L. Solmi et al., “Ultrasound-guided fine needle biopsy of pancreatic masses: results of a multicenter study,” American Journal of Gastroenterology, vol. 93, no. 8, pp. 1329–1333, 1998. View at Publisher · View at Google Scholar · View at Scopus
  14. T. L. Benning, J. F. Silverman, L. A. Berns, and K. R. Geisinger, “Fine needle aspiration of metastatic and hematologic malignancies clinically mimicking pancreatic carcinoma,” Acta Cytologica, vol. 36, no. 4, pp. 471–476, 1992. View at Google Scholar · View at Scopus
  15. A. Fritscher-Ravens, P. V. J. Sriram, C. Krause et al., “Detection of pancreatic metastases by EUS-guided fine-needle aspiration,” Gastrointestinal Endoscopy, vol. 53, no. 1, pp. 65–70, 2001. View at Publisher · View at Google Scholar · View at Scopus
  16. K. D. Dilip, T. M. Abdulaziz, I. H. Bahiya, A. B. Khalida, and A. Rana, “Pancreatic metastasis in a case of small cell lung carcinoma: diagnostic role of fine-needle aspiration cytology and immunocytochemistry,” Journal of Cytology, vol. 28, pp. 226–229, 2011. View at Google Scholar
  17. V. K. Arora, N. Singh, S. Chaturvedi, and A. Bhatia, “Significance of cytologic criteria in distinguishing small cell from non-small cell carcinoma of the lung,” Acta Cytologica, vol. 47, no. 2, pp. 216–220, 2003. View at Google Scholar · View at Scopus
  18. J. M. Winter, A. K. Narang, A. S. Mansfield et al., “Resectable pancreatic small cell carcinoma,” Rare Tumors, vol. 3, no. 1, pp. 13–17, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. M. B. Aslam and N. Sahasrabudhe, “Cytokeratin (CK7 and CK20) switching in the natural history of pulmonary small cell carcinoma: an interesting but unpublished phenomenon,” Journal of Clinical Pathology, vol. 64, no. 4, pp. 367–368, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. X. Lin, R. S. Saad, T. M. Luckasevic, J. F. Silverman, and Y. Liu, “Diagnostic value of CDX-2 and TTF-1 expressions in separating metastatic neuroendocrine neoplasms of unknown origin,” Applied Immunohistochemistry and Molecular Morphology, vol. 15, no. 4, pp. 407–414, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. N. G. Ordóñez, “Value of thyroid transcription factor-1 immunostaining in distinguishing small cell lung carcinomas from other small cell carcinomas,” American Journal of Surgical Pathology, vol. 24, no. 9, pp. 1217–1223, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. D. R. Swarts, F. C. Ramaekers, and E. J. Speel, “Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities,” Biochimica et Biophysica Acta, vol. 1826, no. 2, pp. 255–271, 2012. View at Google Scholar