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Case Reports in Oncological Medicine
Volume 2012, Article ID 619348, 5 pages
http://dx.doi.org/10.1155/2012/619348
Case Report

Recurrent Thrombotic Thrombocytopenic Purpura-Like Syndrome as a Paraneoplastic Phenomenon in Malignant Peritoneal Mesothelioma: A Case Report and Review of the Literature

Division of Hematology, Department of Medicine, Jackson Memorial Hospital/Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, 1475 NW 12th Avenue Suite 3300, Miami, FL 33136, USA

Received 22 August 2012; Accepted 11 September 2012

Academic Editors: J. Kleeff and R. Yamamoto

Copyright © 2012 Francisco Socola et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Moschcowitz, “An acute febrile pleiochromic anemia with hyaline thrombosis of the terminal arterioles and capillaries: an undescribed disease. 1925,” Mount Sinai Journal of Medicine, vol. 70, no. 5, pp. 352–355, 2003. View at Google Scholar
  2. T. J. Torok, R. C. Holman, and T. L. Chorba, “Increasing mortality from thrombotic thrombocytopenic purpura in the United States—analysis of national mortality data, 1968–1991,” American Journal of Hematology, vol. 50, no. 2, pp. 84–90, 1995. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Franchini, “Thrombotic microangiopathies: an update,” Hematology, vol. 11, no. 3, pp. 139–146, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. J. N. George, “Evaluation and management of patients with thrombotic thrombocytopenic purpura,” Journal of Intensive Care Medicine, vol. 22, no. 2, pp. 82–91, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Furlan, R. Robles, M. Galbusera et al., “Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome,” New England Journal of Medicine, vol. 339, no. 22, pp. 1578–1584, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Kojouri, S. K. Vesely, and J. N. George, “Quinine-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: frequency, clinical features, and long-term outcomes,” Annals of Internal Medicine, vol. 135, no. 12, pp. 1047–1051, 2001. View at Google Scholar · View at Scopus
  7. S. L. Allford, B. J. Hunt, P. Rose, and S. J. Machin, “Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias,” British Journal of Haematology, vol. 120, no. 4, pp. 556–573, 2003. View at Google Scholar · View at Scopus
  8. D. Patschan, O. Witzke, U. Dührsen, R. Erbel, T. Philipp, and S. Herget-Rosenthal, “Acute myocardial infarction in thrombotic microangiopathies - Clinical characteristics, risk factors and outcome,” Nephrology Dialysis Transplantation, vol. 21, no. 6, pp. 1549–1554, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. X. L. Zheng, R. M. Kaufman, L. T. Goodnough, and J. E. Sadler, “Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura,” Blood, vol. 103, no. 11, pp. 4043–4049, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. G. A. Rock, K. H. Shumak, N. A. Buskard et al., “Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group,” The New England Journal of Medicine, vol. 325, no. 6, pp. 393–397, 1991. View at Google Scholar
  11. C. L. Bennett, C. J. Davidson, D. W. Raisch, P. D. Weinberg, R. H. Bennett, and M. D. Feldman, “Thrombotic thrombocytopenic purpura associated with ticlopidine in the setting of coronary artery stents and stroke prevention,” Archives of Internal Medicine, vol. 159, no. 21, pp. 2524–2528, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. C. L. Bennett, J. M. Connors, J. M. Carwile et al., “Thrombotic thrombocytopenic purpura associated with clopidogrel,” New England Journal of Medicine, vol. 342, no. 24, pp. 1773–1777, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. J. N. George, “The Oklahoma thrombotic thrombocytopenic purpura-hemolytic uremic syndrome registry: a program for patient care, education and research,” Transfusion, vol. 44, no. 9, pp. 1384–1392, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. E. Rivaud, M. A. Massiani, F. Vincent, E. Azoulay, and L. J. Couderc, “Valacyclovir hydrochloride therapy and thrombotic thrombocytopenic purpura in a HIV-infected patient [11],” Archives of Internal Medicine, vol. 160, no. 11, pp. 1705–1706, 2000. View at Google Scholar · View at Scopus
  15. J. N. George, X. Li, J. R. McMinn, D. R. Terrell, S. K. Vesely, and G. B. Selby, “Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome following allogeneic HPC transplantation: a diagnostic dilemma,” Transfusion, vol. 44, no. 2, pp. 294–304, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. K. K. Francis, N. Kalyanam, D. R. Terrell, S. K. Vesely, and J. N. George, “Disseminated malignancy misdiagnosed as thrombotic thrombocytopenic purpura: a report of 10 patients and a systematic review of published cases,” Oncologist, vol. 12, no. 1, pp. 11–19, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. M. A. Howard, L. A. Williams, D. R. Terrell, D. Duvall, S. K. Vesely, and J. N. George, “Complications of plasma exchange in patients treated for clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome,” Transfusion, vol. 46, no. 1, pp. 154–156, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Brook and B. E. Konwaler, “Thrombotic thrombocytopenic purpura association with metastatic gastric carcinoma and a possible auto-immune disorder,” California Medicine, vol. 102, pp. 222–227, 1965. View at Google Scholar · View at Scopus
  19. E. Tapp and A. Ralston, “Thrombotic microangiopathy associated with squamous carcinoma,” British Medical Journal, vol. 4, no. 677, pp. 209–210, 1969. View at Google Scholar · View at Scopus
  20. M. Aksoy, S. Erdem, and M. Tahsinoglu, “Microangiopathic hemolytic anemia due to adenocarcinoma of the stomach,” New Istanbul Contribution to Clinical Science, vol. 11, no. 2, pp. 103–107, 1975. View at Google Scholar · View at Scopus
  21. R. M. Hansen and G. A. Hanson, “Gastric carcinoma in young people. A case report and review of the literature,” American Journal of Gastroenterology, vol. 74, no. 6, pp. 497–503, 1980. View at Google Scholar · View at Scopus
  22. D. Podzamczer, L. Carreras, E. Condom, J. M. Baucells, and A. Vidaller, “Microangiopathic hemolytic anemia associated with pulmonary adenocarcinoma,” Journal of the American Medical Association, vol. 254, no. 18, pp. 2554–2555, 1985. View at Google Scholar · View at Scopus
  23. M. Eugene, G. Deray, P. Cacoub, A. Achour, and A. Baumelou, “Hemolytic uremic syndrome and prostatic adenocarcinoma,” Clinical Nephrology, vol. 27, no. 1, p. 46, 1987. View at Google Scholar · View at Scopus
  24. W. M. Van der Merwe and J. F. Collins, “The haemolytic uraemic syndrome and prostatic carcinoma,” New Zealand Medical Journal, vol. 100, no. 829, pp. 483–485, 1987. View at Google Scholar · View at Scopus
  25. Case Records of the Massachusetts General Hospital, “Weekly clinicopathological exercises. Case 19-1995. A 55 year-old woman with acute respiratory failure and radiographically clear lungs,” The New England Journal of Medicine, vol. 332, no. 25, pp. 1700–1707, 1995. View at Google Scholar
  26. H. Sill, G. Höfler, P. Kaufmann et al., “Angiotropic large cell lymphoma presenting as thrombotic microangiopathy (thrombotic thrombocytopenic purpura),” Cancer, vol. 75, no. 5, pp. 1167–1170, 1995. View at Google Scholar
  27. Y. C. Lin, H. K. Chang, C. F. Sun, and L. Y. Shih, “Microangiopathic hemolytic anemia as an initial presentation of metastatic cancer of unknown primary origin,” Southern Medical Journal, vol. 88, no. 6, pp. 683–687, 1995. View at Publisher · View at Google Scholar · View at Scopus
  28. P. A. Kouides, P. D. Phatak, and S. F. Cramer, “Fatal thrombotic thrombocytopcnic purpura (TTP) presenting concurrently with metastatic multiple endocrine neoplasia (MEN) type I,” Hematopathology and Molecular Hematology, vol. 10, no. 3, pp. 161–170, 1996. View at Google Scholar · View at Scopus
  29. V. Perkovic, N. A. Came, A. P. Grigg, and G. J. Becker, “Haemolytic uraemic syndrome and prostatic cancer,” Australian and New Zealand Journal of Medicine, vol. 29, no. 3, pp. 383–384, 1999. View at Google Scholar · View at Scopus
  30. N. González, E. Ríos, A. Martín-Noya, and J. M. Rodríguez, “Thrombotic thrombocytopenic purpura and bone marrow necrosis as a complication of gastric neoplasm,” Haematologica, vol. 87, no. 1, article ECR01, 2002. View at Google Scholar · View at Scopus
  31. K. Y. Yeh, P. Dunn, J. W. C. Chang, and C. C. Liaw, “Microangiopathic hemolytic anemia in a patient with recurrent anal cancer and liver metastasis,” Chang Gung Medical Journal, vol. 25, no. 10, pp. 706–710, 2002. View at Google Scholar · View at Scopus
  32. S. Mungall and P. Mathieson, “Hemolytic uremic syndrome in metastatic adenocarcinoma of the prostate,” American Journal of Kidney Diseases, vol. 40, no. 6, pp. 1334–1336, 2002. View at Publisher · View at Google Scholar · View at Scopus
  33. J. L. Lee, J. H. Lee, M. K. Kim et al., “A case of bone marrow necrosis with thrombotic thrombocytopenic purpura as a manifestation of occult colon cancer,” Japanese Journal of Clinical Oncology, vol. 34, no. 8, pp. 476–480, 2004. View at Publisher · View at Google Scholar · View at Scopus
  34. H. T. Arkenau, O. Müssig, T. Buhr, H. H. Jend, and R. Porschen, “Microangiopathic hemolytic anemia (MAHA) as paraneoplastic syndrome in metastasized signet ring cell carcinomas: case reports and review of the literature,” Zeitschrift fur Gastroenterologie, vol. 43, no. 8, pp. 719–722, 2005. View at Publisher · View at Google Scholar · View at Scopus
  35. M. T. Pirrotta, A. Bucalossi, F. Forconi et al., “Thrombotic thrombocytopenic purpura secondary to an occult adenocarcinoma,” Oncologist, vol. 10, no. 4, pp. 299–300, 2005. View at Publisher · View at Google Scholar · View at Scopus