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Case Reports in Oncological Medicine
Volume 2012, Article ID 693137, 4 pages
Case Report

Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature

1Department of Neurosurgery, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, Greece
2Department of Pathology, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, Greece

Received 26 July 2012; Accepted 15 September 2012

Academic Editors: J. M. Buchanich, Y.-J. Chen, S. B. Chichareon, and Y. Niibe

Copyright © 2012 Nikolaos A. Paidakakos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Chondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. Vertebral involvement is exceedingly rare and shows a predilection for the thoracic spine. We report the case of a woman with clear cell chondrosarcoma of the thoracic spine, which has been surgically excised, and review the pertinent literature (PubMed). Although it has a reasonably benign biological behavior, clear cell chondrosarcoma needs to be treated as a malignancy. The best treatment for spinal chondrosarcoma is surgery. It should be promptly and adequately resected. Gross-total resection should be the ultimate surgical goal. Radiation therapy should also be considered, especially in the case of subtotal resection or inoperable lesions. In conclusion, it is important to keep in mind this entity in the differential diagnosis of spinal tumors, in order to optimize treatment planning. With adequate treatment, local recurrence rates as low as 20% can be achieved.