Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Oncological Medicine
Volume 2012, Article ID 819546, 4 pages
http://dx.doi.org/10.1155/2012/819546
Case Report

An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis: A Case Report and Review of the Literature

1Office of Medical Education, 4077 5th Avenue, San Diego, CA 92103, USA
23075 Health Center Drive, Suite 102, San Diego, CA 92123, USA

Received 18 September 2012; Accepted 24 October 2012

Academic Editors: J. I. Mayordomo and M. Ryberg

Copyright © 2012 Mark Lazarus et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Hinchey, C. Chaves, B. Appignani et al., “A reversible posterior leukoencephalopathy syndrome,” The New England Journal of Medicine, vol. 334, no. 8, pp. 494–500, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Glusker, L. Recht, and B. Lane, “Reversible posterior leukoencephalopathy syndrome and bevacizumab,” The New England Journal of Medicine, vol. 354, pp. 980–982, 2006. View at Publisher · View at Google Scholar
  3. J. M. Sweany, W. S. Bartynski, and J. F. Boardman, “‘Recurrent’ posterior reversible encephalopathy syndrome: report of 3 cases—PRES can strike twice!,” Journal of Computer Assisted Tomography, vol. 31, no. 1, pp. 148–156, 2007. View at Publisher · View at Google Scholar
  4. P. C. P. Lau and B. Paunipagar, “Posterior reversible encephalopathy syndrome with bevacizumab,” Hong Kong Medical Journal, vol. 17, no. 1, pp. 80–81, 2011. View at Google Scholar · View at Scopus
  5. A. Sandler, R. Gray, M. C. Perry et al., “Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer,” The New England Journal of Medicine, vol. 355, no. 24, pp. 2542–2550, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Ozcan, S. J. Wong, and P. Hari, “Reversible posterior leukoencephalopathy syndrome and bevacizumab,” The New England Journal of Medicine, vol. 354, no. 9, pp. 981–982, 2006. View at Google Scholar · View at Scopus
  7. S. R. Nalluri, D. Chu, R. Keresztes, X. Zhu, and S. Wu, “Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis,” The Journal of the American Medical Association, vol. 300, no. 19, pp. 2277–2285, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Kilickap, H. Abali, and I. Celik, “Bevacizumab, bleeding, thrombosis, and warfarin,” Journal of Clinical Oncology, vol. 21, no. 18, pp. 3542–3543, 2003. View at Google Scholar · View at Scopus
  9. I. Zachary, “Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor,” American Journal of Physiology, vol. 280, no. 6, pp. C1375–C1386, 2001. View at Google Scholar · View at Scopus
  10. B. Y. Y. Tam, K. Wei, J. S. Rudge et al., “VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis,” Nature Medicine, vol. 12, no. 7, pp. 793–800, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. Allen, A. Adlakha, and P. R. Bergethon, “Reversible posterior leukoencephalopathy syndrome after bevacizumab/FOLFIRI regimen for metastatic colon cancer,” Archives of Neurology, vol. 63, no. 10, pp. 1475–1478, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. S. R. Nalluri, D. Chu, R. Keresztes, X. Zhu, and S. Wu, “Risk of venous thromboembolism with the angiogenesisinhibitor bevacizumab in cancer patients: a meta-analysis,” The Journal of the American Medical Association, vol. 300, no. 19, pp. 2277–2285, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. R. B. Schwartz, S. K. Feske, J. F. Polak et al., “Preeclampsia-eclampsia: clinical and neuroradiographic correlates and insights into the pathogenesis of hypertensive encephalopathy,” Radiology, vol. 217, no. 2, pp. 371–376, 2000. View at Google Scholar · View at Scopus
  14. G. Hagemann, T. Ugur, O. W. Witte, and C. Fitzek, “Recurrent posterior reversible encephalopathy syndrome (PRES),” Journal of Human Hypertension, vol. 18, no. 4, pp. 287–289, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. J. E. Fugate, D. O. Claassen, H. J. Cloft, D. F. Kallmes, O. S. Kozak, and A. A. Rabinstein, “Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings,” Mayo Clinic Proceedings, vol. 85, no. 5, pp. 427–432, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. R. J. Levine, S. E. Maynard, C. Qian et al., “Circulating angiogenic factors and the risk of preeclampsia,” The New England Journal of Medicine, vol. 350, no. 7, pp. 672–683, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Clausen, S. Djurovic, F. R. Brosstad, K. Berg, and T. Henriksen, “Altered circulating levels of adhesion molecules at 18 weeks' gestation among women with eventual preeclampsia: Indicators of disturbed placentation in absence of evidence of endothelial dysfunction?” American Journal of Obstetrics and Gynecology, vol. 182, no. 2, pp. 321–325, 2000. View at Google Scholar · View at Scopus
  18. M. E. Chavarría, L. Lara-González, Y. García-Paleta, V. S. Vital-Reyes, and A. Reyes, “Adhesion molecules changes at 20 gestation weeks in pregnancies complicated by preeclampsia,” European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 137, no. 2, pp. 157–164, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Y. Kim, H. M. Ryu, H. Y. Jae et al., “Maternal serum levels of VCAM-1, ICAM-1 and E-selectin in preeclampsia,” Journal of Korean Medical Science, vol. 19, no. 5, pp. 688–692, 2004. View at Google Scholar · View at Scopus
  20. N. Denduluri, S. X. Yang, A. W. Berman et al., “Circulating biomarkers of bevacizumab activity in patients with breast cancer,” Cancer Biology and Therapy, vol. 7, no. 1, pp. 15–20, 2008. View at Google Scholar · View at Scopus
  21. M. Furuya, K. Kurasawa, K. Nagahama et al., “Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia,” Journal of Pregnancy, vol. 2011, Article ID 123717, 10 pages, 2011. View at Publisher · View at Google Scholar
  22. S. Venkatesha, M. Toporsian, C. Lam et al., “Soluble endoglin contributes to the pathogenesis of preeclampsia,” Nature Medicine, vol. 12, no. 6, pp. 642–649, 2006. View at Publisher · View at Google Scholar · View at Scopus