Paraneoplastic Neurological Syndromes: Severe Neurological Symptoms Resulting from Relatively Benign or Occult Tumours—Two Case Reports

Table 1

Some of the known paraneoplastic syndromes with their associated antibodies and malignancies.

Syndrome	Antibodies	Associated malignancies
Cerebellar degeneration	Anti-Hu, Anti-Yo, Anti Ri, Anti CV2, and Anti-GAD, Anti-Tr, Anti-Zic4, Anti-mGluR1, and Anti-VGCC	SCLC, gynaecological, breast, thymoma, and others
Limbic encephalitis	NMDA, VGKC related antibodies, Anti-Hu, Anti-Ma, and Anti-GAD	Gynaecological, germ cell tumours of testis, and SCLC
Opsoclonus myoclonus	Anti- Ri, neuroleukin, gliadin, and Zic2	Gynaecological, breast, and SCLC
Brainstem encephalitis	Anti-Hu, Anti-Ri, and Anti-Ma
Stiff person Syndrome	Antiamphiphysin, Anti-GAD	SCLC, breast,
Myelitis	Anti-Hu, Antiamphiphysin
Peripheral neuropathy	Anti-CV2	SCLC, thymoma, and others
LEMS	Anti-VGCC	SCLC