Case Report

Adult T-Cell Leukemia-Lymphoma during Pregnancy

Table 1

Pertinent laboratory findings.

ResultNormal

Calcium18.4 mg/dL(8.3–10.2)
Ionized calcium11.4 mg/dL(3.0–6.5)
Phosphate2.6 mg/dL(2.3–4.5)
Parathyroid hormone (PTH)<2.5 pg/mL(10–65)
PTH-related protein (PTH-rp)46 pg/mL(14–27)
Vitamin D Total 25(OH)39 ng/mL(30–100)
Creatinine1.06 mg/dL(0.6–1.2)
Uric acid12.2 mg/dL(2.6–8.1)
Angiotensin-converting enzyme (ACE)54(9–67)
Serum protein electrophoresis (SPEP)Negative
Urine protein electrophoresis (UPEP)Negative
Serum pH7.38(7.35–7.45)

Elevated calcium with normal phosphate and PTH levels points against a diagnosis of primary hyperparathyroidism. Normal vitamin D and ACE levels point against a diagnosis of sarcoidosis or granulomatous disease. Creatinine was normal. Uric acid was noted to be elevated. Negative SPEP and UPEP point against a diagnosis of multiple myelomas. A normal serum pH points against a diagnosis of milk-alkali syndrome. Elevated PTH-rp levels are highly suggestive of hypercalcemia of malignancy.