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Case Reports in Oncological Medicine
Volume 2013, Article ID 986517, 3 pages
Case Report

Unusual Metastatic Patterns of Invasive Lobular Carcinoma of the Breast

St. Joseph Hospital, Department of Surgery, 2900 North Lake Shore Drive, Chicago, IL 60657, USA

Received 12 August 2013; Accepted 29 September 2013

Academic Editors: A. Goodman, P. F. Lenehan, C. V. Reyes, M. Romkes, and M. Ryberg

Copyright © 2013 Justin D. Sobinsky et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Invasive lobular carcinoma of the breast has similar patterns of metastatic disease when compared to invasive ductal carcinoma; however, lobular carcinoma metastasizes to unusual sites more frequently. We present a 65-year-old female with a history of invasive lobular breast carcinoma (T3N3M0) treated with modified radical mastectomy and aromatase-inhibitor therapy who underwent a surveillance PET scan, which showed possible sigmoid cancer. Colonoscopy with biopsy revealed a 3 cm sigmoid adenocarcinoma. The patient underwent a lower anterior resection. Pathology showed an ulcerated, invasive moderately differentiated adenocarcinoma extending into but not through the muscularis propria. However, six of seventeen paracolonic lymph nodes were positive for metastatic breast carcinoma (ER+/PR+), consistent with her lobular primary breast carcinoma; there was no evidence of metastatic colon cancer. This case highlights the unusual metastatic patterns of lobular carcinoma.