Case Report

Transcatheter Arterial Chemoembolization and Chemotherapy plus Sorafenib in a Large Hepatocellular Carcinoma with Arterioportal Shunt

Table 1

Managements and outcomes.

Timing from diagnosis (d) ManagementOutcomes

0CT
laboratory
Tumor size: 12.5 × 8.5 cm 
AFP: 6173 ng/mL
5TACE (gelfoam, an emulsion of 5 mL iodized oil and 40 mg doxorubicin, 1000 mg floxuridine, and 20 mg hydroxycamptothecin)Angiography: tumor staining; APS
9Sorafenib (400 mg twice a day)Stopped at 354 days after the diagnosis
18 LaboratoryAFP: 4179 ng/mL
27TACE (gelfoam, an emulsion of 5 mL iodized oil and 40 mg doxorubicin, 1000 mg floxuridine, and 20 mg hydroxycamptothecin)Angiography: tumor shrink; reestablishment of the APS
59CTTumor size: 9.6 × 7.1 cm
84TAC (20 mg hydroxycamptothecin)  

laboratory
Angiography: tumor shrink; reestablishment of the APS;
AFP: 4247 ng/mL
87CTTumor size: 9.0 × 6.0
151TAC (20 mg hydroxycamptothecin)  
laboratory
Angiography: tumor shrink 
AFP: 6281 ng/mL
152CTTumor size: 8.8 × 6.0 cm
209TAC (20 mg hydroxycamptothecin)Angiography: tumor progression
213CTTumor size: 10.7 × 7.1 cm; tumor metastasis in right hepatic lobe; mild ascites
262CTTumor size: 10.9 × 7.4 cm; moderate ascites
335CTTumor size: 14.4 × 8.4 cm; moderate ascites; gastric varices
354CTTumor size: 14.4 × 8.5 cm; moderate ascites; gastric varices; both left and right hepatic lobes were invaded by the tumor
laboratoryAFP: 80442 ng/mL
366Died from liver function failure