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Case Reports in Oncological Medicine
Volume 2014 (2014), Article ID 424568, 3 pages
Case Report

Metastasis of Laryngeal Squamous Cell Carcinoma to Bilateral Thigh Muscles

1Division of Hematology and Oncology, Washington Cancer Institute, Washington, DC 20010, USA
2MedStar Washington Hospital Center, 110 Irving Street, Washington, DC 20010, USA
3Department of Otolaryngology, MedStar Georgetown University Hospital, Washington, DC 20007, USA

Received 14 July 2014; Revised 13 November 2014; Accepted 21 November 2014; Published 14 December 2014

Academic Editor: Gerassimos P. Vandoros

Copyright © 2014 Zarah Lucas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Importance. Laryngeal cancer infrequently results in distant metastases, but metastasis to skeletal muscle is extremely uncommon. Observations. A 55-year-old male presenting with progressive dyspnea and hoarseness was found to have Stage IVA T4aN2cM0 laryngeal cancer and eventually underwent total laryngectomy. Before the patient could be started on adjuvant chemoradiation, the patient developed masses on both thighs. Biopsy revealed metastatic squamous cell carcinoma consistent with the primary laryngeal cancer. He was offered palliative chemotherapy; however, he developed new soft tissue masses to the left of his stoma and in the prevertebral area one week later. He also had new cervical and supraclavicular nodes and a pathological compression fracture of L3. Patient died within 4 months of diagnosis. Conclusions. Distant metastasis such as skeletal metastasis portends a poor prognosis. Further studies are required to determine the best course of treatment in these patients.