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Case Reports in Oncological Medicine
Volume 2014, Article ID 512928, 4 pages
http://dx.doi.org/10.1155/2014/512928
Case Report

Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm

Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, Poland

Received 13 January 2014; Revised 30 July 2014; Accepted 13 August 2014; Published 2 September 2014

Academic Editor: Francesca Micci

Copyright © 2014 Patrycja Zielinska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disorder in the same patient is extremely rare. In the present report, a case of an 81-year-old man who was diagnosed with chronic lymphocytic leukemia and concomitant essential thrombocythemia is presented. We describe the morphologic, immunophenotypic, cytogenetic, and molecular findings in this patient. We also review the current literature.