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Case Reports in Oncological Medicine
Volume 2014 (2014), Article ID 968926, 3 pages
http://dx.doi.org/10.1155/2014/968926
Case Report

A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment

1Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA
2Department of Anatomic and Clinical Pathology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA
3Department of Radiology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA
4Department of Otolaryngology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA

Received 14 March 2014; Accepted 27 May 2014; Published 8 June 2014

Academic Editor: Gerassimos P. Vandoros

Copyright © 2014 Shahzad Ahmad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.