Metastasis of Gastric Signet-Ring Cell Carcinoma to the Urinary Bladder: A Case Report and Review of the Literature

Table 1

Cases of bladder metastasis secondary to gastric cancer in the literature.

Author/year	Number of patients	Age	Gender	Histology/İHC	Interval between primary gastric tumor and bladder metastasis	Distant metastatic sites at the time of diagnosis	Macroscopic features of bladder metastasis	Urinary symptoms	Presence of hydronephrosis	Treatment of bladder metastasis	Prognosis
Saba et al. [8] (1997)	1	52	M	SRCC/no	7 years	Peritoneum, pleura, lymph nodes	Protuberant mass	Hematuria	No	No treatment	Died
Ota et al. [9] (1999)	1	57	F	Adenoca/no	2 years	No distant metastasis	Diffuse wall thickening	Incontinence	Yes	Chemotherapy	Alive after 12-month follow-up
Kim et al. [10] (2001)	3	60	M	Adenoca/no	1 year	No distant metastasis	Protuberant mass	Dysuria, sense of residual urine	NR	NR	NR
		57	F	SRCC/no	15 months	No distant metastasis	Diffuse wall thickening	Dysuria, frequency	NR	NR	NR
		42	M	SRCC/no	2 years	No distant metastasis	Diffuse wall thickening	Dysuria	NR	Total cystectomy	NR
Antunes et al. [11] (2004)	1	63	F	SRCC/no	21 months	Peritoneum	Diffuse wall thickening	Dysuria, lumbar pain	Yes	No treatment	Alive after 8-month follow-up
Matsuhashi et al. [12] (2005)	1	90	F	Adenoca/no	Synchronous metastasis	No distant metastasis	Protuberant mass (in a bladder diverticulum)	Hematuria	No	No treatment	Died 3 months after the diagnosis
Farhat et al. [13] (2007)	1	58	M	Adenoca/no	15 months	No distant metastasis	Protuberant mass	Hematuria	No	TUR	NR
Lim et al. [14] (2011)	1	51	M	Adenoca/no	2 years	Peritoneum, bone	Protuberant mass	Hematuria	Yes	Partial cystectomy	Died 7 months after the surgery
Sharma et al. [15] (2011)	1	30	M	SRCC/no	2 years	No distant metastasis	Protuberant mass	Hematuria	No	TUR, chemotherapy	Alive 5 months after the chemotherapy
Neves et al. [16] (2011)	2	62	F	SRCC/yes	Synchronous metastasis	Peritoneum, ovary (Krukenberg)	Diffuse wall thickening	Dysuria, infrequency, lumbar pain	Yes	No treatment	Died
		41	M	SRCC/no	Synchronous metastasis	No distant metastasis	Protuberant mass	Hematuria	No	Partial cystectomy	Died
András et al. [17] (2013)	1	59	M	Adenoca/yes	10 years	No distant metastasis	Protuberant mass	Hypogastric pain	No	TUR, chemotherapy	NR
Vigliar et al. [18] (2013)	1	38	M	SRCC/yes	7 months	Peritoneum, pleura, lymph nodes	Protuberant mass	Hematuria	Yes	No treatment	Died 2 months after the diagnosis
Kalra et al. [19] (2015)	1	60	M	SRCC/yes	Synchronous metastasis	Peritoneum	Diffuse wall thickening	LUTS	Yes	Chemotherapy	Alive (follow-up NR)
Present case	1	48	M	SRCC/yes	Synchronous metastasis	Peritoneum, lymph nodes	Diffuse wall thickening	Hematuria	Yes	Chemotherapy	Alive 5 months after the diagnosis

M, male; F, female; İHC, immunohistochemical studies; SRCC, signet-ring cell carcinoma; Adenoca, adenocarcinoma; LUTS, lower urinary tract symptoms; TUR, transurethral resection; NR, not reported.