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Case Reports in Oncological Medicine
Volume 2015, Article ID 163727, 3 pages
Case Report

Case Report of a Patient with Left Ventricular Assistance Device Undergoing Chemotherapy for a New Diagnosis of Lung Cancer

1Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA
2Dow University of Health Sciences, Karachi, Sindh 74200, Pakistan
3Johns Hopkins University, Baltimore, MD 21287, USA
4Yale University, New Haven, CT 06510, USA

Received 28 August 2014; Revised 6 March 2015; Accepted 12 March 2015

Academic Editor: Jeanine M. Buchanich

Copyright © 2015 Maliha Khan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The optimal management of cancer in patients with severe heart failure is not defined. This issue is particularly challenging when a diagnosis of limited-stage small cell lung cancer (SCLC) is made incidentally in the context of evaluating patient for candidacy for cardiac transplantation. Limited-stage SCLC is typically managed on a curative therapeutic paradigm with combined modality approach involving chemotherapy and radiation. Even with excellent performance status and good organ function, the presence of severe cardiomyopathy poses significant challenges to the delivery of even single modality approach with chemotherapy or radiotherapy, let alone the typical curative combined modality approach. With mechanical left ventricular devices to provide cardiac support, treatment options for cancer in the setting of advanced heart failure may be improved. Here we discuss the therapeutic dilemma involving a patient with severe cardiomyopathy and left ventricular assistant device (LVAD) who was found to have limited-stage SCLC during the evaluation process for cardiac transplantation.