Case Reports in Oncological Medicine
Volume 2015, Article ID 210643, 4 pages
http://dx.doi.org/10.1155/2015/210643
Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature
1Radiation Oncology Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, Greece
2Breast Surgery Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, Greece
3Clinical Pathology Department, Saint Savvas Anticancer Institute of Athens, Alexandra’s Avenue 171, 11522 Athens, Greece
4Laboratory of Hematology, Panarcadian General Hospital of Peloponnese, Red Cross Street, 22100 Tripoli, Greece
Received 6 November 2014; Accepted 7 January 2015
Academic Editor: Jose I. Mayordomo
Copyright © 2015 Georgios Koukourakis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer. Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a malignant vascular tumor. An excision biopsy and frozen section analysis confirmed the presence of an encapsulated mesenchymal tumor. Its morphology and immunohistochemical marker profile were characteristic for a malignant hemangiopericytoma. Thus, she underwent a tumor excision without an axilla sampling. Approximately one year after the surgery the patient is well without local recurrence or metastasis disease to be observed. We also reviewed the literature and discuss the treatment options, characteristics, and immunophenotype of HPC. Conclusions. The accurate diagnosis of HPC depends on the appropriate histological and immunohistochemical examination. Surgical resection is the treatment of choice and due to scarcity of cases and unpredictable biological behavior of these tumors long term follow-up may be warranted.