Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation

Figure 1

PET scans. (a) Prechemotherapy PET-CT scan (anterior view) demonstrates marked splenomegaly (white arrows), with multiple hypermetabolic foci scattered throughout the spleen and in the retroperitoneum (blue arrow). There was a large aggregate of abnormal foci at the lower edge of the spleen that measured 7 × 6 × 5 cm (black arrow); (b) PET-CT after 6 cycles of CHOP chemotherapy shows no evidence of disease; (c) recurrent hypermetabolic foci and lymphadenopathy involving multiple sites within the liver (black arrow), peritoneum (blue arrow), mediastinum (white arrows), and neck (gray arrow).

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