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Case Reports in Oncological Medicine
Volume 2016, Article ID 7149821, 6 pages
http://dx.doi.org/10.1155/2016/7149821
Case Report

Neuroendocrine Cancer of Rectum Metastasizing to Ovary

1Department of OBG, Kasturba Medical College, Manipal University, Manipal 576104, India
2IVF and Reproductive Biology Centre, Maulana Azad Medical College, New Delhi 110002, India
3Department of Medical Oncology, Kasturba Medical College, Manipal University, Manipal 576104, India
4Department of Surgery, Kasturba Medical College, Manipal University, Manipal 576104, India
5Department of Pathology, Melaka Manipal Medical College, Manipal University, Manipal 576104, India

Received 21 November 2015; Revised 13 March 2016; Accepted 20 April 2016

Academic Editor: Jorg Kleeff

Copyright © 2016 Sapna Vinit Amin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Neuroendocrine carcinomas (NECs) are rare malignancies that originate from the hormone-producing cells of the body’s neuroendocrine system. Rectal high grade NEC (HG-NEC) constituting less than 1% of colorectal cancers can cause large ovarian metastasis that may be the initial presenting complaint. Ovarian Krukenberg tumor from a primary rectal HG-NEC is a very unusual and exceedingly uncommon differential diagnosis for secondary ovarian malignancy. This case report describes one such extremely rare case of a woman who had presented to the gynecology department with features suggestive of ovarian malignancy and was ultimately diagnosed to have Krukenberg tumor originating from neuroendocrine cancer of rectum. We felt this is a good opportunity to spread more light on neuroendocrine neoplasms that are very rare in gynecological practice.