Case Report
Smooth Muscle Tumor Originating in the Pleura: A Case Report and Updated Literature Review
Table 3
Immunohistochemical pattern in pleural spindle cell neoplasms [
6].
| | Tumor | Vimentin | SMA | HHF-35 | SMMHC | Desmin | CD34 | S100 | BCL-2 | CD99 | Cytokeratin |
| | Smooth muscle tumor | + | + | + | + | + | +/− | − | − | − | − | | Solitary fibrous tumor | + | −/+ | −/+ | −/+ | − | + | − | + | + | − | | Metastatic spindle cell carcinoma | +/− | − | − | − | − | − | − | − | − | + | | Synovial sarcoma | + | − | − | − | − | − | − | + | +/− | +/− | | Fibrosarcoma | + | − | − | − | − | − | − | −/+ | − | − | | Malignant peripheral nerve sheath tumor | + | − | − | − | − | − | −/+ | −/+ | − | − | | Sarcomatous mesothelioma | + | − | − | − | −/+ | − | −/+ | −/+ | −/+ | + | | Spindle cell thymoma | − | − | − | − | − | − | − | −/+ | − | + |
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SMA: smooth muscle actin; HHF-35: actin muscle specific; SMMHC, smooth muscle myosin-heavy chain; +, positive staining; +/−, usually positive; −/+, rarely positive; and −, negative.
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