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Case Reports in Oncological Medicine
Volume 2017, Article ID 1023538, 4 pages
Case Report

Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma

Department of Internal Medicine, Zaans Medisch Centrum, Zaandam, Netherlands

Correspondence should be addressed to L. C. van der Wekken; ln.cmsnaaz@w.nekkew

Received 14 December 2016; Revised 22 March 2017; Accepted 28 March 2017; Published 5 April 2017

Academic Editor: Peter F. Lenehan

Copyright © 2017 L. C. van der Wekken and R. J. L. F. Loffeld. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Disseminated intravascular coagulation (DIC) is a syndrome characterised by simultaneous bleeding and thromboembolic formation. Its acute form is associated with severe bacterial infections and hematological malignancies. It has a fulminant presentation with prolonged bleeding times and diffuse thrombosis. On the other hand, chronic DIC can be asymptomatic for long periods of time and can be seen in patients with disseminated malignancies. This case report describes a patient who developed DIC within one week and bled profusely from venipuncture wounds. An underlying hepatogenic metastasised renal cell carcinoma appeared to be the cause. This is an uncommon and diagnostically challenging presentation.