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Case Reports in Oncological Medicine
Volume 2017, Article ID 4296802, 5 pages
Case Report

Rare Presentation of Primary Extramedullary Plasmacytoma as Lip Lesion

1Mount Sinai Hospital, Chicago, IL, USA
2St. Luke’s Hospital St. Louis, MO, USA

Correspondence should be addressed to Mali Him; ude.ussor.stneduts@mihilam

Received 16 September 2016; Revised 1 February 2017; Accepted 6 February 2017; Published 16 March 2017

Academic Editor: Ossama W. Tawfik

Copyright © 2017 Mali Him et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Malignant plasma cell proliferation can be presented as part of disseminated disease of multiple myeloma, as solitary plasmacytoma of bone, or in soft tissue as extramedullary plasmacytoma. Extramedullary plasmacytomas represented approximately 3% of all plasma cell proliferation. Approximately 80% of extramedullary plasmacytomas occur in the head and neck region while the other 4% occur in the skin and to a lesser extent in the lip. In this paper, we report a rare case of primary cutaneous plasmacytoma involving the lip in a 65-year-old male. The patient presented with a nonhealing lower lip sore for the past 3 years. Upon further workup, there was no evidence of multiple myeloma or light chain disease. The patient was treated with radiation therapy and his last follow-up revealed no evidence of multiple myeloma or light chain disease.