Sinonasal Melanoma: A Case Report and Literature Review

Figure 2

Immunohistochemical profile and histology of the lesion. (a) AE1 + AE3. (b) CD 138. (c) CK 8/18. (d) Desmin. (e) HMB 45. (f) S100 (×40)—focal positivity. (g) Vimentin (×20)—diffuse. (h) CD3. (i) CD20. (j) HE ×10. (k) HE ×20. (l) HE ×40. Pleomorphic, polyhedral giant cells with large hyperchromatic nucleoli with a diffuse pattern.

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