Case Report
Successful Use of a Multidisciplinary Approach to Treat a Perforated Duodenal Malignant Lymphoma in an Elderly Patient
Table 1
Cases of perforated duodenal lymphoma reported in Japan.
| Number | Reference | Age/sex | Sites of duodenum | Lymphoma type | Time of perforation | Surgery | Chemotherapy | Radiotherapy | Prognosis | Cause(s) of death |
| 1 | [22] | 65/M | 1st | DLBCL | At presentation | Pancreaticoduodenectomy | CHOP | − | Alive 9+ months | − | 2 | [23] | 61/M | 4th | T-cell lymphoma | After two cycles of SMILE | Argon plasma coagulation | Etoposide+ CHOP SMILE | − | Unknown | − | 3 | [24] | 82/M | 4th | T-cell lymphoma | After 6 cycles of CHOP | Partial resection | CHOP | − | 12 months | Abdominal abscess | 4 | [25] | 70/F | 2nd | DLBCL | At presentation | Simple closure, peritoneal patch | R-CHOP | + | Alive 304 days | Sepsis | 5 | Our case | 75/F | 3rd | DLBCL | Day 21 after surgery, before chemotherapy | Gastrojejunostomy | R R-mini CHP R-CHP R-CHOP | + | Alive 4+ years | − |
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DLBCL = diffuse large B cell lymphoma; R-CHOP = rituximab (R), cyclophosphamide (C), doxorubicin (H), vincristine (O), prednisolone (P); CHP = cyclophosphamide (C), doxorubicin (H), prednisolone (P); SMILE = steroid (S), methotrexate (M), ifosfamide (I), L-asparaginase (L), etoposide (E).
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