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Case Reports in Oncological Medicine
Volume 2018, Article ID 3790106, 4 pages
Case Report

A Rare Case of Metastasis to the Thyroid Gland from Renal Clear Cell Carcinoma 11 Years after Nephrectomy and Concurrent Primary Esophageal Carcinoma

1Department of Internal Medicine, University of Toledo Medical Center, Toledo, OH 43614, USA
2Department of Hematology and Oncology, Rhode Island Hospital, Providence, RI, USA
3Department of Oncology, University of Toledo Medical Center, Toledo, OH 43614, USA
4Department of Pathology, University of Toledo Medical Center, Toledo, OH 43614, USA

Correspondence should be addressed to Mohammad Saud Khan; ude.odelotu@2nahk.dammahom

Received 10 December 2017; Accepted 28 January 2018; Published 2 April 2018

Academic Editor: Katsuhiro Tanaka

Copyright © 2018 Mohammad Saud Khan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Renal cell carcinoma is known to cause metastasis to unusual sites, which can be both synchronous or metachronous. Thyroid gland is a rare site for metastasis, but when it occurs, renal cell carcinoma is the most common primary neoplasm. We report the case of a 81-year-old female patient who had a significant medical history of right clear cell renal carcinoma with adrenal metastasis. She underwent right radical nephrectomy and adrenalectomy followed by radiofrequency ablation of left adrenal metastasis and systemic chemotherapy with sunitinib. Eleven years later, she presented with dysphagia and was found to have distal esophageal adenocarcinoma. On imaging, there was incidental detection of a left renal mass lesion and a right thyroid nodule, which on histopathology and immunohistochemistry were confirmed to be clear cell carcinoma of renal origin.