A Case of Chemotherapy-Refractory “THRLBCL like Transformation of NLPHL” Successfully Treated with Lenalidomide

Figure 1

Haemotoxylin and eosin (H&E) stain (a) at 400x magnification showing a diffuse appearing infiltrate composed of scattered large atypical cells in a background of smaller lymphocytes and histiocytes and (b) at 600x magnification showing lymphocyte predominant cells. (c) CD3 stain highlights abundant background T cells and shows a hint of nodularity (center) shown at 100x magnification. (d) Large tumor cells are strongly positive for PAX5. Note the presence of the nodule of tumor cells in the center.

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