Case Report
Disseminated Intravascular Coagulation as an Initial Manifestation of Metastatic Prostate Cancer Emergently Treated with Docetaxel-Based Chemotherapy
(a) Trend of laboratory abnormalities on 1st admission |
| | PT/INR (seconds) | PTT (seconds) | Fibrinogen (mg/dl) | FDP (μg/ml) | Platelet (per μl) | Event | | Reference range | 12.0-15.0 | 23.0-37.0 | 227-467 | <5 | 150-450 | |
| | Day 1 | 25.1/2.5 | 43.9 | 60 | >20 | 88,000 | days; supportive transfusions | | Day 2 | 18.8/1.60 | 39 | 114 | >20 | 89,000 | | | Day 3 | 18.4/1.56 | 36.9 | 119 | >20 | 99,000 | | | Day 5 | 18.5/1.57 | 35.5 | 104 | >20 | 104,000 | ADT started | | Day 6 | 16.0/1.29 | 28.8 | 149 | >20 | 104,000 | Discharged; advised outpatient follow-up |
|
|
(b) Trend of laboratory abnormalities on 2nd admission |
| | Day 1 | 22.5/2.03 | 52.6 | 98 | >20 | 63,000 | week; restarted ADT | | Day 5 | 25.9/2.45 | 52.9 | 147 | >20 | 51,000 | Supportive transfusions | | Day 10 | 22.1/1.98 | 51.6 | 81 | >20 | 47,000 | Hematuria worsening; supportive transfusions | | Day 11 | 23.5/2.15 | 45.5 | 60 | >20 | 41,000 | | | Day 12 | 30.4/3.03 | 48.4 | 60 | >20 | 36,000 | Chemotherapy started | | Day 13 | 23.5/2.15 | 45.4 | 69 | >20 | 48,000 | | | Day 14 | 20.0/1.74 | 56.8 | 133 | >20 | 35,000 | | | Day 15 | 20.4/1.78 | 53.1 | 152 | >20 | 30,000 | |
|
|
