Case Reports in Oncological Medicine / 2020 / Article / Tab 2

Case Report

Regionally Metastatic Merkel Cell Carcinoma Associated with Paraneoplastic Anti-N-methyl-D-aspartate Receptor Encephalitis

Table 2

Autoimmune paraneoplastic syndromes associated with Merkel cell carcinoma.

Reference(s)Symptoms/syndromeAutoimmune antibodies

Lopez et al. [21]Painless proximal muscle weaknessAnti-Hu/ANNA-1 antibodies
Balegno et al. [22]Paraneoplastic cerebellar ataxiaAntibodies against cerebellar nerve fibers
Greenlee et al. [23]Sensorimotor and autonomic neuropathy, encephalopathyAnti-Hu/ANNA-1 antibodies
Cher et al. [24]Paraneoplastic brainstem encephalitisAntibodies against brain and cerebellum filamentous structures
Eggers et al. [25], Nguyen et al. [26], and Iyer et al. [27]Lambert-Eaton myasthenic syndromeAntibodies against VGCCs
Sharobeam et al. [28]Subacute cerebellar degenerationAnti-Hu/ANNA-1 antibodies
Zhang et al. [29]Paraneoplastic cerebellar degenerationAntibodies against VGCCs
Hocar et al. [30]Severe necrotizing myopathyAnti-Hu/ANNA-1 antibodies
Current caseExpressive aphasia, altered mental status, memory loss, seizures/NMDAR encephalitisAnti-NMDAR antibodies

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