Primary Leiomyosarcoma of the Gallbladder

Figure 2

Pathohistochemical profile. (a) Ligand: normal gallbladder mucosa. (b, c) H&E stain shows proliferation of spindle cells arranged in interlacing bundles, pronounced nuclear atypia, pleomorphism, and many atypical mitotic figures (×200 and ×400, respectively). (d) SMA stain: the neoplastic cells show a strong cytoplasmic staining reaction (×200).

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(b)

(c)

(d)