Unique Presentation of Rosai-Dorfman Disease as Concomitant Appendiceal and Rectal Masses with IgG4-Positive Plasma Cells Diagnosed by Core Needle Biopsy

<div>(a) Histiocytes with characteristic prominent nucleoli and pale abundant cytoplasm (hematoxylin and eosin, 600x). (b) Histiocytes with emperipolesis (hematoxylin and eosin, 600x). (c) Immunohistochemistry of the appendiceal mass with S-100 highlighting large histiocytes with prominent nucleoli (600x). (d) Immunohistochemistry of the appendiceal mass with CD68 highlighting large areas of histiocytes. (e) Immunohistochemistry of the appendiceal mass with IgG4-positive cells.</div>

Case Reports in Oncological Medicine

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Figure 5

Figure 5: Unique Presentation of Rosai-Dorfman Disease as Concomitant Appendiceal and Rectal Masses with IgG4-Positive Plasma Cells Diagnosed by Core Needle Biopsy 

Figure 5 | Unique Presentation of Rosai-Dorfman Disease as Concomitant Appendiceal and Rectal Masses with IgG4-Positive Plasma Cells Diagnosed by Core Needle Biopsy 