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| # | Author (year) | Age | Pathology | PC | Gestational age at dx | Clinical presentation | Treatment during pregnancy | Pregnancy outcome | Staging | Treatment postpregnancy | Time from pregnancy end to treatment | PCI | CC score | Complications | Breast-feeding | Status | Child |
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| 1 | Present case #1 | 31 | LAMN | Yes | 2nd Tx (20 weeks) | Routine prenatal screening | Appy, omentectomy, RSO, peritoneal bx | Spontaneous vaginal delivery (38 weeks) | MRI abd/pelv at 20 weeks; CT chest/abd/pelv after delivery | CRS/HIPEC (Mit-C) | 4 mos | 37 | CC-1 | POD 15: portal vein thrombosis POD 30: rectal bleeding | 4 mos+12 mos milk donor | 5 yrs, NED | Healthy |
| 2 | Haase et al. (2010) [5] | 30 | Well-differentiated mucinous adenocarcinoma | Yes | 2nd Tx (17 weeks) | Routine prenatal screening | Appy, RSO, omental bx | Early induce vaginal delivery (35 weeks) | CT after delivery | CRS/HIPEC (Mit-C) + EPIC (5-FU); adjuvant XELOX x8 cycles | 2.5 weeks | 28 | CC-1 | Neutropenia, prolonged ileus (NGT, TPN), DVT | - | 5 yrs, NED | Healthy |
| 3 | Chiverto et al. (2012) [6] | 36 | Infiltrating mucinous adenocarcinoma (T3N1M1a) | Yes | 2nd Tx (18 weeks) | Abdominal pain x4 days | Dx lap, open appy | Terminated with misoprostol | Colonoscopy, CT chest/abd/pelv after termination | CRS/HIPEC (5-FU + Oxaliplatin; adjuvant FOLFOX x6 Mos | - | 6 | Complete | - | NA | 10 mos, NED | NA |
| 4 | Canuto et al. (2016) [7] | 38 | Well-differentiated mucinous adenocarcinoma (pT4apN1) | Yes | 1st Tx | Routine prenatal screening (R ovarian mass) | Laparoscopic R adnexectomy, peritoneal washing/bx (16 weeks, 4 days) | RDS prophylaxis; early C-section (33 weeks, 5 days) | - | CRS/HIPEC (Mit-C + Cisplatin); adjuvant FOLFOX x8 cycles | 2 mos | - | No residual tumor | - | - | 2 yrs, NED | Healthy |
| 5 | Sebire et al. (2000) [8] | 29 | Moderately differentiated adenocarcinoma; liver metastasis | Yes | 3rd Tx (29 weeks) | Abdominal pain, vomiting, UTI | None | C-section (30 weeks) | Abd US (29 weeks); fine-needle liver bx | CRS; adjuvant 5-FU/Epirubicin/carboplatin | 0 days (at C-section) | - | Residual tumor | - | - | 6 mos, AWD | Healthy |
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| 6 | Donnenfeld et al. (1986) [24] | 25 | Perforated invasive grade 1 mucinous adenocarcinoma | No | 3rd Tx (31 weeks) | Acute appendicitis with peritonitis | Urgent open appy, abscess drain | Induced vaginal delivery (33 weeks) | Chest X-ray, CT abd, colonoscopy 3 days after delivery | R hemicolectomy | 9 days | NA | NA | None | - | 30 days | Healthy |
| 7 | Morgan et al. (2004) [25] | 30 | Well-differentiated mucinous adenocarcinoma, negative peritoneal washings | No | 2nd Tx (26 weeks) | Acute abdomen | Urgent open R hemicolectomy | Spontaneous vaginal delivery (at term) | - | None | NA | NA | NA | None | - | 36 mos, NED | - |
| 8 | Zeteroğlu et al. (2003) [26] | 35 | Non-perforated mucinous appendiceal cyctadenocarcinoma | No | 2nd Tx (21 weeks) | Symptoms of acute appendicitis | Urgent appy | Terminated with misoprostol (21 weeks) | - | R hemicolectomy, omentectomy | 3 days | NA | NA | None | NA | 1 yr, NED | NA |
| 9 | Casey et al. (2003) [27] | 36 | Perforated appendiceal mucious cystadenoma | No | 2nd Tx (21 weeks) | Symptoms of acute appendicitis | Open appy | - | - | None | NA | NA | NA | - | - | - | - |
| 10 | Kalu and Croucher (2004) [28] | 42 | Mucus adenoma with mucocele | No | 1st Tx (5 weeks) | US due to vaginal bleeding | None | Spontaneous miscarriage (anembryonic pregnancy) (7 weeks) | US at 5 weeks (adnexal mass); US in 3 Mos (enlarging ovarian mass) | Laparotomy/appy | 3 mos | NA | NA | None | NA | - | NA |
| 11 | Idris et al. (2015) [29] | 35 | Mucocele | No | 2nd Tx (22 weeks) | Symptoms of acute appendicitis | Open appy | Spontaneous vaginal delivery (at term) | - | None | NA | NA | NA | None | - | 1 yr, NED | - |
| 12 | Gilboa et al. (2008) [30] | 31 | Carcinoid tumor | No | 1st Tx (9 weeks) | Symptoms of acute appendicitis | Appy | Spontaneous miscarriage (5 days post-op) | - | - | - | NA | NA | - | - | - | NA |
| 13 | Louzi et al.§ (2006) [31] | 36 | Well-differentiated carcinoid tumor | No | 3rd Tx (34 weeks) | Symptoms of acute appendicitis | Urgent appy | Vaginal delivery (35 weeks) | - | R hemicolectomy | 2 weeks | NA | NA | - | - | 23 mos, NED | Healthy |
| 14 | Piatek et al. (2016) [32] | 28 | Well-differentiated carcinoid with gangrenous appendicitis (KI-67: <1%) | No | 2nd Tx (25 weeks) | Symptoms of acute appendicitis | Appy | Spontaneous vaginal delivery (38 weeks) | MRI abd at 29 weeks, normal 24-hour urine 5-HIAA; whole body SPECT 3 Mos after delivery | None | NA | NA | NA | None | - | 1 yr, NED | Healthy |
| 15 | Berrios (1965) [33] | 23 | Carcinoid tumor | No | 1st Tx (2 months) | Symptoms of acute appendicitis | Appy | Spontaneous vaginal delivery (at term) | Negative liver scan during pregnancy | None | NA | NA | NA | - | - | 23 mos, NED | Healthy |
| 16 | Berrios (1965) [33] | 26 | Carcinoid tumor | No | 1st Tx (10 weeks) | Symptoms of ruptured ectopic pregnancy | Bleeding luteum cyst, incidental appy | - | - | None | NA | NA | NA | - | - | No FU | - |
| 17 | Pitiakoudis et al. (2008) [34] | 24 | Carcinoid tumor (0.5 cm) | No | 3rd Tx (32 weeks) | Symptoms of acute appendicitis | Appy | Spontaneous vagina delivery (39 weeks) | - | - | - | NA | NA | None | - | - | Healthy |
| 18 | Korkontzelos (2005) [35] | 23 | Carcinoid tumor (2.2 cm) | No | 2nd Tx (16 weeks) | Symptoms of acute appendicitis | Urgent appy | C-section (36 weeks) | - | R hemicolectomy | 0 days (at C-section) | NA | NA | - | - | - | Healthy |
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