Synchronous Occurrence of Splenic Pleomorphic Mantle Cell Lymphoma and Esophageal Adenocarcinoma with Overexpression of BCL1 Protein

Figure 1

Pleomorphic mantle cell lymphoma involves the spleen. (a) Diffuse infiltration of the splenic red pulp by large-sized tumor cells with clumped chromatin and conspicuous nucleolus (100x). (b) Immunostain for CD20 demonstrates membranous pattern positivity (200x). (c) Immunostain for CD5 reveals membranous pattern positivity (400x). (d) Immunostain for CD23 exhibits partial membranous pattern positivity (400x). (e) Immunostain for cyclin D1 demonstrates partial nuclear positivity (400x). (f) Immunostain for SOX11 presents with partial nuclear pattern positivity (400x).

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