Synchronous Occurrence of Splenic Pleomorphic Mantle Cell Lymphoma and Esophageal Adenocarcinoma with Overexpression of BCL1 Protein

Figure 3

Esophageal adenocarcinoma arises from Barrett’s esophagus. (a) Poorly differentiated invasive adenocarcinoma involving the submucosa of the esophagus (200x). (b) The adenocarcinoma originates from overlying Barrett’s esophagus with high-grade dysplasia (200x). (c) Immunostain for AE1/AE3 demonstrates strong cytoplasmic and membrane pattern positivity (200x). (d) Esophagus, immunostain for cyclin D1 demonstrates strong nuclear pattern positivity (200x).

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(b)

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