Metastatic Lesion of the Tibia from Renal Cell Carcinoma

Figure 3

(a–d) The micrograph of a clear cell renal cell carcinoma H&E stain. This image demonstrates the optically clear tumor cells with uniform small nuclei without nucleolar ranged in an alveolar pattern. Cells with clear cytoplasm, typically arranged in nests. Nuclear atypia is common. Water-clear or optically clear cells (due to glycogen content) arranged in nests in “chicken wire” vasculatures. Visible subcapsular changes in the area of the kidney cortex. Numerous extravasations are visible in the vascular glomeruli (a, b). Metastasis of renal cell carcinoma. Histological microphotograph showing neoplastic cells with prominent nucleoli. Ankle joint and metastasis of renal cell carcinoma H&E sections (c, d). Scal bar: (a) 200 μm; (b–d) 100 μm. The samples were analyzed morphologically and photographed under an Olympus BX43 light microscope equipped with an Olympus SC50 digital camera.

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