Systemic Bevacizumab for Severe Recurrent Respiratory Papillomatosis

Figure 1

(a) Extensive papillomas along the epiglottis, bilateral aryepiglottic folds, and bilateral true and false cords with extension into the subglottis (left) and residual small papillomas on the laryngeal surface of the epiglottis after 2 months and 3 treatments of bevacizumab (right). (b) Severe laryngeal papillomas of the left larynx (left) and disappearance of disease after 3 months and 4 treatments of bevacizumab (right). There is a small scar band in the posterior glottis (black arrow).

(a)

(b)