Hepatocellular Carcinoma Metastasis to the Orbit in a Coinfected HIV+ HBV+ Patient Previously Treated with Orthotopic Liver Transplantation: A Case Report
Figure 2
(a) The tumor is composed of cords of cells resembling hepatocytes surrounded by a looser hypocellular fibrous stroma containing prominent sinusoidal vessels. (E.E, 100x). (b) Semithin section: polygonal cells in trabecular pattern, with large nuclei and prominent nucleoli and many intracytoplasmic small vesicles (Polychr. sec. Tolivia, 400x). (c) The neoplastic cells showed strong and diffuse immunoreactivity for OCH1E5. (I.I.C., 400x). (d) Electron microscopic appearance: malignant hepatocytes with numerous mitochondria, abundant glycogen, and large nuclei with prominent nucleoli. Bile canaliculi with stubby microvilli and cell junctions were also evident (TEM, 1800x).
