Case Report

A Patient with Corneal Epithelial Disorder That Developed after Administration of a Latanoprost Generic, but Not a Brand-Name Drug, Eye Drop

Table 1

Differences between Latanoprost eye drops (Kaken pharmaceutical Co., Ltd.) and Xalatan eye drops.

Latanoprost eye dropsXalatan eye drops

AdditivesBenzalkonium chloride additive (concentration not open to the public)Benzalkonium chloride additive (0.02%)
Polyethylene glycol monostearateIsotonizing agent
Polyoxyl 40 stearateDibasic sodium phosphate hydrate
Isotonizing agentSodium dihydrogen phosphate anhydrous
Dibasic sodium phosphate hydrate
Sodium dihydrogen phosphate anhydrous

Osmotic pressure ratio0.9–1.01.0

StorageRoom temperature storage/protection from light2–8°C/protection from light