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Case Reports in Ophthalmological Medicine
Volume 2012, Article ID 967561, 3 pages
Case Report

Loss of Retinal Function and Pigment Epithelium Changes in a Patient with Common Variable Immunodeficiency

1Department of Ophthalmology, Copenhagen University Hospital Roskilde, 4000 Roskilde, Denmark
2Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark

Received 27 July 2012; Accepted 5 September 2012

Academic Editors: A. Ferreras and D. K. Roberts

Copyright © 2012 Jakob Halborg and Torben L. Sørensen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Common variable immunodeficiency (CVID) has only scarcely been associated with ocular symptoms and rarely with retinal disease. In this case we describe a patient with distinct morphological and functional alterations in the retina. The patient presents with characteristic changes in retinal pigment epithelium, autofluorescence, and electrophysiology.