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Case Reports in Ophthalmological Medicine
Volume 2013, Article ID 875989, 3 pages
Case Report

Confocal Microscopy in Biopsy Proven Argyrosis

1Department of Ophthalmology, Ege University Faculty of Medicine, 35100 Izmir, Turkey
2Department of Pathology, Ege University Faculty of Medicine, 35100 Izmir, Turkey

Received 17 June 2013; Accepted 3 July 2013

Academic Editors: A. A. Bialasiewicz, S. M. Johnson, and G. Savini

Copyright © 2013 Melis Palamar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate the confocal microscopy findings of a 46-year-old male with bilateral biopsy proven argyrosis. Materials and Methods. Besides routine ophthalmologic examination, anterior segment photography and confocal microscopy with cornea Rostoch module attached to HRT II (Heidelberg Engineering GmbH, Heidelberg, Germany) were performed. Findings. Squamous metaplastic changes on conjunctival epithelium and intense highly reflective extracellular punctiform deposits in conjunctival substantia propria were detected. Corneal epithelium was normal. Highly reflective punctiform deposits starting from anterior to mid-stroma and increasing through Descemet’s membrane were evident. Corneal endothelium could not be evaluated due to intense stromal deposits. Conclusion. Confocal microscopy not only supports diagnosis in ocular argyrosis, but also demonstrates the intensity of the deposition in these patients.