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Case Reports in Ophthalmological Medicine
Volume 2015, Article ID 153831, 4 pages
http://dx.doi.org/10.1155/2015/153831
Case Report

Pseudotumoral and Multiple Retinal Pigment Epithelium Proliferation in Vogt-Koyanagi-Harada Disease

1Vitreoretinal Surgery Department, Clinica de Ojos, Maracaibo, Venezuela
2Retina Division, Wilmer Eye Institute, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA

Received 24 July 2015; Revised 14 September 2015; Accepted 27 September 2015

Academic Editor: Shigeki Machida

Copyright © 2015 Juan B. Yepez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report a case of pseudotumoral retinal pigment epithelium (RPE) proliferation in Vogt-Koyanagi-Harada (VKH) disease, in a 50-year-old female who presented with a juxtapapillary and peripheral subretinal hyperpigmented lesions in the left eye and “sunset glow fundus,” hyperpigmented striae, and multiple atrophic chorioretinal spots in the periphery. The darkly pigmented exuberant larger subretinal mass extended to the periphery with associated subretinal fibrosis. This patient demonstrated the entire clinical presentation of VKH disease, which tends to course with a chronic, bilateral, granulomatous panuveitis and exudative retinal detachment associated with poliosis, vitiligo, alopecia, and central nervous system and auditory signs. Our case is unique for the presence of exuberant, pseudotumoral RPE proliferation at the juxtapapillary region and peripheral area. Although this complication has rarely been reported, a high index of suspicion is warranted for early diagnosis and avoids unnecessary treatments of a pseudotumor.