Phenotypic Spectrum of Granular Corneal Dystrophy Type II in Two Italian Families Presenting an Unusual Granular Corneal Dystrophy Type I Clinical Appearance

Figure 4

Case , the mother. Slit-lamp examination revealed the presence of bilateral diffuse linear or lattice, granular, and stellate opacities (a). The IVCM evaluation of the mother’s cornea reveals the presence of multiple hyperreflective stellate deposits (maybe of amyloid origin) with needle-shaped dense aspects surrounding low-reflective internal core (maybe of hyaline origin) containing hyperreflective spots (b and c). Time domain OCT corneal scans provided a wide visualization of the cornea revealing the topographic localization and the depth of corneal deposits (d).

(a)

(b)

(c)

(d)