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Case Reports in Ophthalmological Medicine
Volume 2016 (2016), Article ID 8740264, 3 pages
http://dx.doi.org/10.1155/2016/8740264
Case Report

Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman

University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, Italy

Received 31 December 2015; Accepted 30 March 2016

Academic Editor: J. Fernando Arevalo

Copyright © 2016 Chiara De Giacinto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods. A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination. The patient displayed unilateral involvement, with severe visual loss. However, visual acuity improved significantly after four days of intravenous steroid therapy with 500 mg/day of methylprednisolone. Conclusions. Optic neuritis is one of the rare complications associated with the mumps, measles, and rubella vaccine. It may be a toxic reaction to the nonviral component of the vaccine, but the exact etiology is unknown. Postvaccination neuritis is generally bilateral and usually affects children. In adults, unilateral optic neuritis is usually correlated with multiple sclerosis (MS).