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Case Reports in Ophthalmological Medicine
Volume 2017 (2017), Article ID 5804965, 3 pages
Case Report

Late Onset Descemet Membrane Detachment after Radial Keratotomy Resolved with Medical Therapy

1Eye Center, Humanitas University, Humanitas Clinical and Research Hospital, Rozzano, Italy
2St. Paul’s Eye Unit, Royal Liverpool University Hospital, Liverpool, UK

Correspondence should be addressed to P. Rosetta

Received 7 April 2017; Revised 25 September 2017; Accepted 4 October 2017; Published 31 October 2017

Academic Editor: Nicola Rosa

Copyright © 2017 P. Rosetta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To report a case of a Descemet membrane’s (DM) detachment after radial keratotomy (RK). Methods. A patient (male) underwent RK (16 cuts) 20 years before referring to the Eye Center of Humanitas (Milan) for a progressive visual loss. The slit-lamp examination showed severe corneal stromal edema and a large DM detachment in the lower half of the cornea. Anterior segment optical coherence tomography (AS-OCT) and endothelial cells count confirmed DM detachment and endothelial cells damage. Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) was planned and topical hypertonic therapy was prescribed before the surgery. Results. Eight months later, the patient mentioned a spontaneous increase in visual acuity; the slit-lamp examination and the AS-OCT displayed a recovery of corneal transparency with a resolution of DM detachment. Conclusions. This is the first report of spontaneous DM detachment with severe corneal edema after RK. We suggest that hypertonic therapy may reduce DM detachment and restore corneal transparency.