Bilateral Iris Mammillations in Amblyopic Eyes without Oculodermal Melanocytosis or Neurofibromatosis

Table 1

Modified table from Ragge et al. (1996) summarizing the case reports of iris mammillations [1].

No	Age/sex	Ethnic origin	Ocular involvement	Iris involvement	Melanosis oculi	Naevus	Ocular disease	Other disease	Journal	Year	Author
1	8F	Caucasian	U	P	N	Y	Myopia	None	Eye	1996	Ragge
2	8F	Hispanic	B	T	N	N	High myopia	CHD, cleft palate, marfanoid habitus	Eye	1996	Ragge
3	9M	Hispanic	U	P	Y	Y	Esotropia and amblyopia of other eye	Seizures	Eye	1996	Ragge
4	20M	Asian-Indian	B	P	Y	N	Iris hamartomas	Neurofibromatosis type 1	Eye	1996	Ragge
5	7F	Hispanic	B	ST	N	N	Optic neuritis	TB frontal arachnoid cyst	Eye	1996	Ragge
6	10F	Middle Eastern	B	T	Y	N	Calcified ciliary body mass	Mother also had bilateral iris elevations	Eye	1996	Ragge
7	5F	Hispanic	B	T	Y	N	Congenital glaucoma	Phakomatosis pigmentovascularis Iib	Eye	1996	Ragge
8	28M	Asian (Indian)	B	ST	N	N	None	None	Eye	1996	Ragge
9	2M	N. African	B	T	Y	N	None	Ectopic Mongolian spot, preauricular skin tag, abnormal rib	Eye	1996	Ragge
10	8F	-	U	T	Y	N	Choroidal melanoma, Retinal detachment	None	Arch Ophthalmol	2000	Gündüz
11	1M	Caucasian	B	-	N	N	None	None	J Fr Ophtalmol	2006	Kharrat
12	8M	Caucasian	B	-	N	N	None	None	J Fr Ophtalmol	2006	Kharrat
13	5M	Caucasian	U	-	Y	N	Ipsilateral ocular melanocytosis	None	J Fr Ophtalmol	2006	Kharrat
14	9F	Türkler	B	P	N	N	Optic nerve damage, Persistent pupillary membrane	None	Clin Exp Optom	2007	Ozdamar
15	7F	Asian (Malaysian)	B	T	N	N	None	Siblings, CAH, Clitoris acne, Labioscrotal hyperpigmentation	BMJ Case Reports	2010	Peyman
16	7F	Asian (Malaysian)	B	T	N	N	None	Siblings, CAH, Clitoris acne, Labioscrotal hyperpigmentation	BMJ Case Reports	2010	Peyman
17	5M	Caucasian	U	T	Y	N	Scleral pigmentation	None	Arch Soc Esp Oftalmol	2014	Marugán B
18	8F	Hispanic	B	T	N	N	None	None	Arch Soc Esp Oftalmol	2014	Marugán B
19	16F	Caucasian	B	T	N	N	None	None	Arch Soc Esp Oftalmol	2014	Marugán B
20	22F	Hispanic	B	P	Y	N	Eyelid trichilemmoma	Twins, Cowden syndrome	JAAD Case Reports	2016	Suaiti
21	22F	Hispanic	B	P	Y	N	Eyelid trichilemmoma	Twins, Cowden syndrome	JAAD Case Reports	2016	Suaiti
22	12M	Hispanic	B	ST	Y	Y	Monolateral ocular melanocytosis, Glaucoma, Choroidal haemangioma	Sturge-Weber Syndrome, naevus flammeus of the face	Csse Rep Ophthalmol	2017	Plateroti
23	10F	Asian, (Japanese)	B	T	N	N	Amblyopia	None	Case Rep Ophthalmol Med	This Case	Yamamoto, Mimura

Age, years; M, male; F, female; U, unilateral; B, bilateral; P, partial; T, total; ST, subtotal; Y, yes; N, no; CHD, congenital heart disease; CAH, congenital adrenal hyperplasia.