Case Reports in Ophthalmological Medicine / 2021 / Article / Tab 1

Case Series

Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center

Table 1

Diagnostic criteria of VKH.

No history of penetrating ocular trauma or surgery preceding the initial onset of uveitis
No clinical or laboratory evidence suggestive of other ocular disease entities
Bilateral ocular involvement
Early manifestationsLate manifestations
Evidence of a diffuse choroiditis (with or without anterior uveitis, vitreous inflammatory reaction, or optic disc hyperemia)
Focal areas of subretinal fluid or bullous serous retinal detachments
History suggestive of prior presence of findings
Ocular depigmentation; sunset glow fundus or Sugiura’s signs
Equivocal fundus findings:
Focal areas of delay in choroidal perfusion, multifocal areas of pinpoint leakage, large placoid areas of hyperfluorescence, pooling within subretinal fluid, and optic nerve staining
Diffuse choroidal thickening
Other ocular signs:
(a) Nummular chorioretinal depigmented scars
(b) Retinal pigment epithelium clumping and/or migration
(c) Recurrent or chronic anterior uveitis
Neurological/auditory findings (may have resolved by time of examination); meningismus, tinnitus, or cerebrospinal fluid pleocytosis
Integumentary finding (not preceding onset of central nervous system or ocular disease), alopecia, or poliosis, or vitiligo