Macular Changes in a Mucopolysaccharidosis Type I Patient with Earlier Systemic Therapies

Figure 2

SD-OCT horizontal and vertical scans of fovea in the right eye (a, b). It demonstrates foveal increased thickness of hyperreflective band signal at the ELM, with intact myoid, ellipsoid, and interdigitation zones, RPE, and Bruch’s membrane. In the parafoveal and perifoveal region, it demonstrated a progressive loss of interdigitation and ellipsoid zones, myoid zone, and ELM and thinning of the outer nuclear layer. SD-OCT horizontal scan, close to the fovea (c), demonstrated a small cyst in ONL, INL, and GCL (arrows). SD-OCT: spectral domain optical coherence tomography; ELM: external limiting membrane; RPE: retinal pigment epithelium; ONL: outer nuclear layer; INL: inner nuclear layer; GCL: ganglion cell layer.

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