An Unusual Case of Clear Cell Chondrosarcoma with Very Late Recurrence and Lung Metastases, 29 Years after Primary Surgery

Table 1

Summary of published studies on clear cell chondrosarcomas with more than five patients and clinical data.

Study

Patients

Intralesionally resected/local recurrence

Time of recurrence

Wide resection/local recurrence

Time of recurrence

Time of metastasis (range)

Number of lethal cases

Location of metastasis

Longest survival after recurrence

Longest survival after metastasis

Longest time to recurrence

Longest time to metastasis

Unni et al. 1976 [3]

16

44%/86%

2.1 y (0.3 y–5 y)

54%/none

—

1 y (1 y–1.2 y)

5/16

Lung; Bone; Brain

7.3 y

1.2 y

5 y

1.2 y

Le Charpentier et al. 1979 [5]

5

20%/100%

3 y

80%/none

—

2 y

1/5

Lung

10 y

2 y

3 y

2 y

Bjornsson et al. 1984 [2]

47

32%/86%

Range 0.2 y–5 y

52%/16%

4 y (2 y–6 y)

Range 2 y–12 y

7/47

Lung; Bone

13 y

6 y

6 y

12 y

Ayoub et al. 1999 [6]

6

50%/66%

3.9 y (2.8 y–5 y)

50%/33%

19 y

4.2 y

19 y

1 y

Itälä et al. 2005 [1]

16

44%/71%

1.7 y (0.1 y–1.9 y)

56%/none

—

8.1 y (4–16.4 y)

1/16

Lung; Bone

5-year survival 50%

8.4 y

1.9 y

16.4 y

Corradi et al. 2006 [42]

6

33%/100%

1.2 y (0.3 y–2 y)

67%/none

—

2.5 y (0.6 y–5 y)

0/6

Bone

5.4 y

4.8 y

7.5 y

9.7 y

Donati et al. 2008 [41]

18

28%/40%

4.4 y (1.0 y–11 y)

72%/17%

Range 2.2 y–10 y

Range 1 y–11 y

0/18

Bone; Soft tissue

5 y

11 y

10 y