Case Report

A Case of C5 Vertebral Chordoma in a 73-Year-Old Patient with More Than 8 Years of Follow-Up after Total Piecemeal Spondylectomy

Figure 3

Histological and immunohistochemical features of the tumor. (a) Hematoxylin and eosin stain showing pathognomonic physaliphorous cells with multivacuolated cytoplasm. The appearance of chordoma consists of cords and islands of tumor cells arrayed in a distinctly lobular fashion, with mucus-filled cytoplasm. (b, c, d) The tumor cells demonstrating positive immunostaining with AE1/AE3 (b), epithelial membrane antigen (EMA) (c), and KI-67 expression (d). Scale bar of all the panels: 100 μm.
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