Osteosarcomatous Transformation in the Setting of Mazabraud’s Syndrome: A Case Report and Review of the Literature

Figure 4

Microscopic hematoxylin and eosin stain sections of right femur tissue. (a) Osteosarcoma with osteoblastic component including neoplastic osteoid formation (triangle) and (b) markedly pleomorphic tumor cells. (c) Fibrous dysplasia with irregular bony spicules and trabeculae (BT) with fibrous stroma (ST). (d) Myxoma composed of hypocellular and hypovascular stromata (ST) containing abundant myxoid matrix and bland spindled cells.

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(b)

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