Continuous Local Antibiotics Perfusion Therapy for Acute Deep Infections after Open Fractures

Table 3

Summary of renal function and maximum serum level of gentamicin.

Patient number	Cre (mg/dL); Pre	Cre (mg/dL); Post^†	BUN (mg/dL); Pre	BUN (mg/dL); Post^†	eGFR (mL/min/1.73m^2); Pre	eGFR (mL/min/1.73m^2); Post^†	Maximum serum level of gentamicin (μg/mL)
1	0.67	0.60	11	11	123.8	139.7	Not tested
2	0.71	0.81	20	16	121.2	104.9	Not tested
3	0.7	0.63	12	9	103.3	115.9	0.6
4	0.76	0.80	12	12	63.7	60.2	0.4
5	0.45	0.40	12	15	106.6	121.2	0.2
6	0.63	0.59	16	15	88.1	94.7	0.9
Average	0.65	0.64	13.8	13.0	101.1	106.1	0.525

Cre: creatinine; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; “Pre” indicates immediately before starting CLAP therapy. ^†“Post” indicates within two days after finishing CLAP therapy.