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Case Reports in Otolaryngology
Volume 2015, Article ID 749890, 4 pages
http://dx.doi.org/10.1155/2015/749890
Case Report

IgG4-Related Nasal Pseudotumor

1Department of Otorhinolaryngology, Lovisenberg Diakonale Hospital, 0440 Oslo, Norway
2Department of Pathology, Oslo University Hospital, Rikshospitalet, 0372 Oslo, Norway
3Department of Otorhinolaryngology, Telemark Hospital, 3710 Skien, Norway

Received 4 August 2014; Revised 13 January 2015; Accepted 18 January 2015

Academic Editor: Kenichi Takano

Copyright © 2015 L. K. Døsen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

IgG4-related disease is recognized as one form of autoimmune pancreatitis. During the last ten years, it has also been described in several other organs. We present two patients with lesions showing a histological picture of fibrosis and lymphoplasmacytic infiltrations with abundant IgG4 positive plasma cells at hitherto unreported symmetrical nasal locations. The symmetrical complex consisted of one central lesion in the anterior nasal septum and the two others in each of the lateral nasal walls. The lesions extended from the anterior part of the inferior concha into the vestibulum and caused severe nasal obstruction.